东京健康长寿医学研究所大泽郁朗教授Ikuroh Ohsawa, Tokyo MetropolitanInstitute of Gerontology
大泽郁朗是2007年在《自然医学》杂志发表氢分子生物学里程碑论文的第一作者，当时他在日本医学大学老年病研究所太田成男教授课题组，氢分子领域10数篇关键论文都是他作为作者完成，后来关于动脉硬化的保护效应的论文他仍作为第一作者，最近他的课题组发表用于精子保护效应的研究。
1. Nakata K, Yamashita N, Noda Y, Ohsawa I.Stimulation of human damagedsperm motility with hydrogen molecule. Med Gas Res. 2015 Jan 10;5(1):2.
2. Iio A, Ito M, Itoh T, Terazawa R, Fujita Y, Nozawa Y, Ohsawa I, OhnoK, Ito M. Molecular hydrogen attenuates fatty acid uptake and lipidaccumulation through downregulating CD36 expression in HepG2 cells. Med GasRes. 2013 Mar 1;3(1):6.
3. Terasaki Y, Ohsawa I, Terasaki M, Takahashi M, Kunugi S, Dedong K,Urushiyama H, Amenomori S, Kaneko-Togashi M, Kuwahara N, Ishikawa A, KamimuraN, Ohta S, Fukuda Y. Hydrogen therapy attenuates irradiation-induced lungdamage by reducing oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2011Oct;301(4):L415-26.
4. Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular hydrogen improvesobesity and diabetes by inducing hepatic FGF21 and stimulating energymetabolism in db/db mice. Obesity (Silver Spring). 2011 Jul;19(7):1396-403.
5. Oharazawa H, Igarashi T, Yokota T, Fujii H, Suzuki H, Machide M,Takahashi H, Ohta S, Ohsawa I. Protection of the retina by rapid diffusion ofhydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusioninjury. Invest Ophthalmol Vis Sci. 2010 Jan;51(1):487-92.
6. Suzuki Y, Sano M, Hayashida K, Ohsawa I, Ohta S, Fukuda K. .Are theeffects of alpha-glucosidase inhibitors on cardiovascular events related toelevated levels of hydrogen gas in the gastrointestinal tract? FEBS Lett. 2009Jul 7;583(13):2157-9.
7. Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, MaesawaS, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K. Molecular hydrogen isprotective against 6-hydroxydopamine-induced nigrostriatal degeneration in arat model of Parkinson's disease. Neurosci Lett. 2009 Apr 3;453(2):81-5.
8. Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S. Molecularhydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatinwithout compromising anti-tumor activity in mice. Cancer Chemother Pharmacol.2009 Sep;64(4):753-61.
9. Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S. Consumption ofhydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.Biochem Biophys Res Commun. 2008 Dec 26;377(4):1195-8.
10.Nagata K, Nakashima-Kamimura N, Mikami T, Ohsawa I, Ohta S..Consumption of molecular hydrogen prevents the stress-induced impairments inhippocampus-dependent learning tasks during chronic physical restraint in mice.Neuropsychopharmacology. 2009 Jan;34(2):501-8.
11.Hayashida K, Sano M, Ohsawa I, Shinmura K, Tamaki K, Kimura K, Endo J,Katayama T, Kawamura A, Kohsaka S, Makino S, Ohta S, Ogawa S, Fukuda K..Inhalation of hydrogen gas reduces infarct size in the rat model of myocardialischemia-reperfusion injury. Biochem Biophys Res Commun. 2008 Aug15;373(1):30-5.
12.Fukuda K, Asoh S, Ishikawa M, Yamamoto Y, Ohsawa I, Ohta S. Inhalationof hydrogen gas suppresses hepatic injury caused by ischemia/reperfusionthrough reducing oxidative stress. Biochem Biophys Res Commun. 2007 Sep28;361(3):670-4.
13.Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, YamagataK, Katsura K, Katayama Y, Asoh S, Ohta S. Hydrogen acts as a therapeutic antioxidantby selectively reducing cytotoxic oxygen radicals. Nat Med. 2007Jun;13(6):688-94. |
